Aquatic Life Sciences Archives (Volume 1 Issue 2)

Lulus Mualimin, Mentari Sekar Arum. In Silico Study of Bioactive Compounds Fucoxanthin and Fucoidan from Sargassum echinocarpum as Anti-Cancer Agents Targeting Caspase-3 Protein. Aquatic Life Sciences. 2025; 1(2):45-52.

Abstract: Cancer is a complex disease characterized by disruptions in cell regulation mechanisms, leading to abnormal or uncontrolled cell growth and the ability to spread to other parts of the body. The caspase-3 protein plays a crucial role in the apoptotic mechanism and is a key target in cancer therapy. B Show more...

Abstract: Cancer is a complex disease characterized by disruptions in cell regulation mechanisms, leading to abnormal or uncontrolled cell growth and the ability to spread to other parts of the body. The caspase-3 protein plays a crucial role in the apoptotic mechanism and is a key target in cancer therapy. Bioactive compounds from the brown alga Sargassum, such as fucoidan and fucoxanthin, show significant potential as anticancer agents through mechanisms including apoptosis induction, cell cycle arrest, and metastasis inhibition. This study employed an in silico method to investigate the interaction between the natural ligands fucoidan and fucoxanthin and the target protein caspase-3, simulating their potential as anticancer drug candidates. The analysis revealed distinct interactions for each ligand with the target protein, as indicated by their binding affinity values. The interaction between fucoidan and caspase-3 resulted in a binding affinity value of ∆G -4.7 kcal/mol, which was lower in effectiveness compared to the interaction between fucoxanthin and caspase-3, with a binding affinity value of ∆G -7.7 kcal/mol. This suggests that fucoxanthin exhibits stronger anticancer activity through its interaction with caspase-3 compared to fucoidan. Meanwhile, toxicity tests showed that fucoidan has a lower toxicity profile than fucoxanthin, particularly in terms of LD₅₀ values and active/inactive toxicity parameters. These findings indicate that fucoxanthin has potential as anticancer drug candidates. Further research is needed to optimize their therapeutic efficacy and safety profiles. Show less...

Molecular docking Toxicity profile Therapeutic efficacy

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Abdul Jaleel K., Prakash P. S., Pooja K., Manjula K. T. Invasive Teak Defoliator Hyblaea puera Outbreak Threatens Mangrove Ecosystems in Kerala, India: Implications for Biodiversity and Coastal Resilience. Aquatic Life Sciences. 2024; 1(2):39-44.

Abstract: Mangroves play a vital role in coastal resilience by supporting biodiversity, preventing soil erosion, and sustaining local livelihoods. This study reports the first major outbreak of the invasive moth Hyblaea puera (teak defoliator) on mangroves in Kannur and Kasaragod Districts, Kerala, India. The Show more...

Abstract: Mangroves play a vital role in coastal resilience by supporting biodiversity, preventing soil erosion, and sustaining local livelihoods. This study reports the first major outbreak of the invasive moth Hyblaea puera (teak defoliator) on mangroves in Kannur and Kasaragod Districts, Kerala, India. The larvae caused severe defoliation of Avicennia officinalis, Kerala's dominant mangrove species, leaving vast areas with a burned appearance. This infestation threatens the ecological and socio-economic value of mangroves, impacting their protective functions and local biodiversity. Similar outbreaks have occurred in Maharashtra's Airoli and Vashi Creek, primarily affecting Avicennia marina. The epidemic-level infestation in Kerala was noted in 2024, especially during monsoon and post monsoon months, with larvae also targeting species like Acanthus ilicifolius, Bruguiera cylindrica, Derris trifoliata, Derris trifoliata, Rhizophora mucronata, and Volkameria inermis. Pest identification was confirmed via mitochondrial COI gene sequencing. Natural predators, including birds, snails, spiders, and parasitoids, were observed, indicating potential for biological control. Future studies will focus on assessing the ecological impact and exploring management strategies like biological control, chemical treatments, and physical removal to protect mangrove ecosystems in Kerala, India. Show less...

Hyblaea puera Teak defoliator Avicennia officinalis Mangrove conservation Pest management Defoliation COI gene sequencing

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Ihsan Sanggar Rahman. An Observation-Based Study of Silver Pomfret (Trachinotus blochii) Hatchery Practices at Lombok Marine Aquaculture Center. Aquatic Life Sciences. 2024; 1(2):32-38.

Abstract: Abstract This observation-based study evaluates the seed production practices of Silver Pomfret (Trachinotus blochii) at the Lombok Marine Aquaculture Center (BPBL Lombok), West Nusa Tenggara, Indonesia. BPBL Lombok is a key facility for marine aquaculture, focusing on breeding species such as the Show more...

Abstract: Abstract This observation-based study evaluates the seed production practices of Silver Pomfret (Trachinotus blochii) at the Lombok Marine Aquaculture Center (BPBL Lombok), West Nusa Tenggara, Indonesia. BPBL Lombok is a key facility for marine aquaculture, focusing on breeding species such as the star snapper in an environment with optimal water quality and well-equipped facilities. The study investigates broodstock management, including hormonal induction for spawning, and the growth and grading processes of fry at various developmental stages. Stocking densities were adjusted based on size, and water quality parameters were closely monitored to ensure the survival and growth of the fry. The study also examines the impact of feed management, gonad maturation, and water quality control on the survival rate (SR) of T. blochii fry, with the results indicating a typical SR of 50%, with optimal management. The findings contribute valuable insights for improving Silver Pomfret breeding practices and highlight the importance of sustainable aquaculture techniques for the development of marine fish farming in Indonesia. Show less...

Keyword: Breeding practice Sustainable aquaculture Water quality control Seed production

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Juahir Juahir. Aquaculture Management of Blue Swimming Crab (Portunus pelagicus) in Boncong Bancar Marine Farming Facility, Tuban Regency, East Java Province, Indonesia. Aquatic Life Sciences. 2024; 1(2):27-31.

Abstract: This study was conducted at the Boncong Bancar Marine Farming Facility in Tuban, East Java, focusing on Blue Swimming Crab (Portunus pelagicus) aquaculture. As a high-value seafood commodity with crucial export markets, the study aimed to enhance knowledge and skills, providing valuable insights for Show more...

Abstract: This study was conducted at the Boncong Bancar Marine Farming Facility in Tuban, East Java, focusing on Blue Swimming Crab (Portunus pelagicus) aquaculture. As a high-value seafood commodity with crucial export markets, the study aimed to enhance knowledge and skills, providing valuable insights for students and stakeholders. It emphasized the need for sustainable aquaculture to reduce reliance on wild harvesting, as Blue Swimming Crab demand exceeds natural supply. The research adopted a descriptive approach, including biological characteristics, survival rates, behavior, water quality, and feeding techniques according to MFF Boncong standards. Water quality measurements resulted in an average pH of 6 to 8, temperatures not exceeding 33°C, dissolved oxygen levels between 5.0 ppm and 8.4 ppm, and salinity between 30–35 ppt. In summary, Blue Swimming Crab aquaculture offers a profitable business opportunity, contributing to the country’s foreign exchange reserves, and warrants close attention from fisheries experts. Show less...

Water quality measurement Seafood commodity Crab aquaculture

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