Research Article Open Access

Friday, 3 November 2023

Phytochemical profiling, heavy metals composition, in silico aphrodisiac potential, and ADMET study of Gardenia erubescens

Enoch Buba Badgal et al.

Abstract: This study aimed to explore the phytochemical profile, heavy metal composition, in silico aphrodisiac potential, and ADMET study of Gardenia erubescens due to its folkloric acclaimed aphrodisiac use. The phytochemicals were quantified gravimetrically while the identification of bioactive compounds was carried out using a combined Gas spectrophotometer-mass spectrophotometer (GC-MS). Heavy metals were quantified using an atomic absorption spectrophotometer while the aphrodisiac and ADMET studies ...

Review Open Access

Thursday, 2 November 2023

Exploring the potential impact of herbal antioxidants on human cardiovascular diseases

Wrestwar D Marak et al.

Abstract: The body's antioxidant system efficiently neutralizes reactive oxygen species, which are intermediates formed during routine metabolic activity. Oxidative stress resulting from an imbalance in this neutralization process is known to be a key factor in many human ailments, including atherosclerosis and various cardiovascular diseases. Observational epidemiological research conducted over the past several decades has shown that consumption of vegetables and fruits rich in vitamins and antioxidants...

Research Article Open Access

Monday, 2 October 2023

Alpha lipoic acid improves memory and antioxidant enzymes activity in diabetic Wistar rats

Usman Adamu Garkuwa et al.

Abstract: Diabetes mellitus (DM) and oxidative stress are among the leading causes of memory loss and dementia. Dietary supplements have been used to manage many disorders. This research aimed to determine the effect of alpha lipoic acid (ALA) on memory and oxidative stress in diabetic Wistar rats. 30 rats were grouped into six (5 in each). Diabetes was induced using a high-fat diet followed by a single low dose of streptozotocin (40 mg/kg) intraperitoneally. Group I served as normoglycemic control (1 mL/...

Review Open Access

Saturday, 30 September 2023

A narrative review on clinical trials showing contraindicated drugs with grapefruit juice

Ahmed Abd El-Moniem Amer et al.

Abstract: Medication and food are frequently consumed together. However, some foods have interactions with medicines by changing key regulators of systemic medication availability. Their consumption is linked to interactions with a wide range of medications. One of the most significant beverages that can be harmful when combined with certain medicines is grapefruit juice. Furanocoumarins' mechanism-based suppression of intestinal cytochrome P450 3A4, which increases the bioavailability of drugs that are s...

Research Article Open Access

Tuesday, 5 September 2023

Efficacy of sunscreen gel infused with giant tiger prawn (Penaeus monodon) head extract

Adilah Marwa et al.

Abstract: Excessive sunlight exposure can lead to various minor skin disorders, including sunburn and the development of chronic skin malignancies. One effective preventive measure against these adverse effects is the use of sunscreen. Sunscreen can be derived from natural sources, such as the astaxanthin compound in giant tiger prawns (Penaeus monodon). This study aimed to formulate a sunscreen gel from giant tiger prawn head extract that meets good physical gel standards. Additionally, the study sought ...