Research Article Open Access

Wednesday, 23 July 2025

NLP Analysis of Mannan-Based Drug Delivery Trends

Reza Pratama et al.

Abstract: Mannan, a polysaccharide derived from various sources, has gained attention for its biocompatibility and potential in targeted drug delivery. Since its initial use in 1911 as an ointment base, mannan has been applied in cancer therapy, vaccine development, and as an antimicrobial agent. However, research is still largely dominated by in vitro and preclinical studies, with few clinical trials conducted to date. This study aims to provide an overview of mannan's advancements, its uses in drug deli...

Research Article Open Access

Monday, 30 June 2025

Sustainable Harvest of Large Pelagic Fish in the Western Sumatra Sea

Desta Hutagaol et al.

Abstract: Large pelagic fish such as tuna, skipjack, and mackerel are key export commodities for fishers at Bungus Oceanic Fishing Port due to high demand and their importance in processed fish products. This study analyzed trends, sustainable potential, and utilization levels of these resources in the western Sumatra Sea. Research conducted from March 17 to April 1, 2023, used a descriptive quantitative survey and literature review, with catch and effort data from 2015 to 2022 processed using Microsoft E...

Review Open Access

Monday, 12 May 2025

Effect of Gene Polymorphisms on Oral Antidiabetic Drug Response in Patients With Type 2 Diabetes Mellitus

Nur Rahmi Hidayati et al.

Abstract: Diabetes mellitus is currently one of the global health threats. The prevalence and incidence of this disease continue to increase, both in industrialised and developing countries, including Indonesia. There are different types of DM marker gene polymorphisms in each racial group. These genetic variations contribute to the response of oral antidiabetic drugs. This article aims to conduct a narrative review of the influence of gene polymorphisms on oral antidiabetic drug response in patients with...

Public Insight Open Access

Thursday, 13 February 2025

Peningkatan Pemahaman Masyarakat Mengenai Penggunaan Antibiotik untuk Cegah Resistensi di Kampung Rawa Panjang

Munir Alinu Mulki et al.

Abstract: Antibiotics are substances or compounds that are either synthetically produced or naturally generated by microorganisms, especially fungi. They are used as inhibitors of other microorganisms. The use of antibiotics in humans is based on their minimal toxicity to the human body. Inaccurate and prolonged use of antibiotics can lead to the development of resistance. A step taken to minimize antibiotic resistance is the introduction of the 2023 PITIK (Penyuluhan Informasi Tentang Antibiotik) program...

Research Article Open Access

Friday, 27 December 2024

Development of Chitosan-Based Antimicrobial Hydrogel Incorporating Polyvinylpyrrolidone and PHMG

Ivan Ivanov et al.

Abstract: This study focuses on the development of a chitosan-based hydrogel incorporating polyvinylpyrrolidone and polyhexamethylene guanidine hydrochloride for the rehabilitation of damaged and contaminated skin. The thermal properties of chitosan-containing films were characterized by measuring the glass transition temperature (Tg) using differential scanning calorimetry. Due to challenges in accurately determining the Tg of chitosan from experimental and literature data, an additional method, dynamic ...