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Sciences of Phytochemistry
Sciences of Phytochemistry

e-ISSN 2962-553X
p-ISSN 2962-5793
DOI 10.58920/sciphy

Sciences of Phytochemistry (SciPhy) is an international, peer-reviewed open-access journal published by ETFLIN. SciPhy aims to offer a widely visible and highly indexed platform for scholars and intellectuals, especially the youth, to share their opinions, insights and works.

Important journal information

Publication fee: Zero, No article processing charge
Publishing model: Gold Open Access
Free access: Immediate
Issues per year: 2 issues
Peer review: Double blind
Review speed: 7-30 days
Acceptance to publication: 0-2 days
Start year: 14 June 2022
Language: English
Journal DOI: https://doi.org/10.58920/sciphy
Contact: sciphy@etflin.com

The review speed largely depends on the availability of reviewers 

Scope

SciPhy accepts research, review, mini-review, opinion/perspective, technical note, case report, clinical trial and conference proceedings that falls within the scope of the journal. Click this link to submit an article

  1. Pharmacognosy and Phytochemistry
    Pharmacognostical characterization of medicinal plants. Phytochemical screening of plant extracts, fractions and purified fractions. Isolation, purification and characterization of phytocompounds.
  2. Pharmacology and Toxicology
    Evaluation of the pharmacological activity and toxicity of medicinal plants, phytocompounds and herbal formulations.
  3. Ethnobotany and Ethnopharmacology
    Field survey and documentation of traditionally important medicinal plants used by ethnic/tribal groups.
  4. Nutraceuticals
    Foods or vegetables having medicinal value. Medicinal plants that are regularly consumed as vegetables.
  5. Pharmaceutics
    Development, characterization, and evaluation of herbal formulations wherein medicinal plant(s) or phytocompound(s) acts as the main active ingredient. Isolation and characterization of polymers from plants having pharmaceutical importance. Application of nanotechnology for herbal formulation development, increasing bioavailability of phytocompounds and site-specific delivery of phytocompounds.
  6. In-silico
    Application of computer-aided drug design, bioinformatics, machine learning, artificial intelligence, network pharmacology, and systems biology to evaluate the in-silico pharmacological activity (or ADMET profile) of phytocompounds. Lead identification from a phytocompound library. Identification of potential drug targets for phytocompounds. Articles reporting in-silico design and screening of synthetic analogs/semi-synthetic derivatives of phytocompounds shall be considered only if the newly designed compounds outperforms the original phytocompounds in all areas.
  7. Clinical
    Clinical studies evaluating the safety and efficacy of medicinal plants, phytocompounds and herbal formulations. Pharmacovigilance of medicinal plants shall cover drug-phytocompound interactions and adverse drug reactions due to consumption of medicinal plant products.
  8. Method development
    Development and validation of bioassay, analytical, qualitative or quantitative methods with significant utility in the field of pharmacognosy and phytochemistry.
  9. Miscellaneous
    Medicinal plant biotechnology, medicinal plant chemistry, cultivation of medicinal plants and commercialization of medicinal plant products.
Note: Articles that are out of the journal scope will be rejected immediately.

EDITOR-IN-CHIEF

James H. Zothantluanga (M.Pharm)
Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh 786004, Assam, India

Editor-in-Chief's Profile


EDITORS

The editorial board of SciPhy comprises of 12 professionals from 6 different countries. Our editors bring a diverse range of knowledge, skills and experiences to the table, enabling us to provide a broad perspective on various topics.

Dr. Bethsebie Lalduhsaki Sailo (M.Sc, Ph.D.)
Department of Surgery, School of Medicine, Yale University, USA

Dr. Jonathan Lalsiamthara (M.V.Sc, Ph.D.)
Oregon Health & Science University, Portland, USA

Dr. Ejiofor InnocentMary IfedibaluChukwu (Ph.D.)
Nnamdi Azikiwe University, Awka, Anambra State, Nigeria

Dr. Mohnad Abdalla (Ph.D.)
Pediatric Research Institute, Children’s Hospital, Shandong University, Jinan, China

Dr. Sanchaita Rajkhowa (M.Sc., Ph.D.)
Centre for Biotechnology and Bioinformatics, Dibrugarh University, Assam, India

Prof. Samir Chtita (Ph.D.)
Department of Chemistry, Université Hassan II de Casablanca, Morocco

Prof. H. Lalthanzara (M.Sc., Ph.D.)
Department of Zoology, Pachhunga University College, Mizoram, 
India

Dr. Hannah S. Lalnunpuii (MBBS)
Ebenezer Medical Center, Chawnpui, Aizawl, Mizoram, India
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Faruk Jayanto Kelutur (B.Sc., M.Pharm)
Department of Chemistry, Pattimura University, Ambon, Indonesia

F. Nghakliana (M.Sc.)
Department of Zoology, Mizoram University, Mizoram, India

Himangshu Sarma (M.Pharm)
Sophisticated Analytical Instruments Facility, Girijananda Chowdhury Institute of Pharmaceutical Sciences, Guwahati, Assam, India

Mary Lalfakzuali (M.Sc.)
Krishi Vigyan Kendra (KVK) Lengpui, Mamit, Mizoram, India

Flowchart of Submission Process
ETFLIN Journal Submission

AUTHORS SHOULD READ THE JOURNAL GUIDELINES CAREFULLY 

SciPhy requests all authors to use the journal template for drafting their manuscripts.
Download Journal Template

Submission of manuscript
SciPhy uses an online submission system. Do not submit your papers through mail.

New authors are requested to:

  • Click log in (top right corner)
  • Select New author
  • Register
  • Submit manuscripts

Submission checklist

  1. Graphical abstract (optional)
  2. Manuscript (containing tables and figures)
  3. Supplementary files (if any)

Manuscripts that will receive direct editorial rejections without peer-review

  1. Poor grammar
  2. Poor discussion of results
  3. Studies that are too simple
  4. Not following the instructions for authors at all
  5. Obvious ethical issues

Tracking of submitted papers
The submitting authors can track the real-time status of their manuscripts by logging into the online submission system.

Abstract
Unstructured abstract not more than 250 words. The abstract should briefly highlight the background, methods, main results, and conclusions of the study.

Graphical abstract (optional)

  • Graphical abstract is not mandatory but is highly encouraged.
  • Size: Height and width = should fit within the first page of the SciPhy template (if possible)
  • Quality: Minimum of 300 dpi
  • File type: JPG or PNG. The file type of figures must be uniform for all the figures. If the graphical abstract is in JPG, all the other figures should be in the JPG format.

Types of Manuscript

  1. Original articles (no word limit)
  2. Reviews (no word limit)
  3. Short communications (up to 3000 words excluding references)
  4. Mini-reviews (up to 3000 words excluding references)
  5. Opinion papers (up to 2000-2500 words excluding references)

If there are cases wherein the word limits are exceeded, the Editor-in-Chief will examine the paper and may recommend it for further consideration. However, this will depend on the quality of the manuscript.

Manuscript Format

1. The body of research (original) papers should strictly follow the guidelines:

  • Introduction
  • Experimental section
  • Results & Discussion
  • Conclusion

2. The body of short communications should follow the guidelines:

  • Introduction (including methods written in brief)
  • Results and Discussion
  • Conclusion

3. The body of review (review/mini-review/opinion) papers may be divided to fit personal requirements. However, it should always have an introduction and conclusion

  • Introduction
  • Title 1
  • Title 2
  • Title 3
  • Conclusion

Figures

  • Size: Height = should fit within a single page of the SciPhy template, width = should fit within the SciPhy template
  • Quality: Minimum 300 dpi
  • File type: JPG or PNG. The file type of figures must be uniform for all the figures. If figure 1 is in JPG, all the other figures should be in the JPG format.

Reproduction of figures
To reproduce a figure (already published in a paper in any journal) in SciPhy, a permission must be obtained from the corresponding author of the paper from which the original figures are to be taken. In the manuscript, the statement (for example) 'Reproduced with permission from Hmar et al. 2022' should accompany the figure caption. If a figure is reproduced without permission, it will be considered as plagiarism and the authors will be asked to rectify the same.

Tables
Tables must be created with the insert table feature of the Microsoft word. The detailed design of the table is given in the SciPhy template.

Equations
Equations must be created with the insert equation feature of the Microsoft word.

Other details (title, authors, affiliation, abstract, keywords, tables, figures, section, sub-section, in-text citation, funding, acknowledgement, conflict of interest, authors contribution) are available on the journal template.

Software to reduce grammatical errors
The use of grammarly (or any other software) is encouraged to help the authors to minimize grammatical errors.

Disclosure for the use of artificial intelligence (AI)
AI models like ChatGPT do not qualify as authors for SciPhy. The use of AI should be limited to correction of grammatical errors or improvement of language. AI should not be used to entirely to draft a paper. If authors are using AI to improve the quality of the grammar or language, they should make a new section heading as "Disclosure for the use of artificial intelligence". Under this section, the authors should state that "An AI model (name of the model) was used to improve the quality of the grammar/language". This section should come after the Acknowledgement section. 

Reference managing software
Authors are encouraged to use software such as Mendeley, etc. to assist them while arranging the references.

Reference Style

Article with volume, issue and page numbers
Umar AK, Wathoni N, Zothantluanga JH. Liposome-polymer complex for drug delivery system and vaccine stabilization. Heliyon (2022) 8(3):89-34. 

Article without volume, issue or page numbers
Umar AK, Zothantluanga JH, Aswin K, Maulana S, Chetia D. Antiviral phytocompounds "ellagic acid" and "(+)-sesamin" of Bridelia retusa identified as potential inhibitors of SARS-CoV-2 3CL pro using extensive molecular docking, molecular dynamics simulation studies, binding free energy calculations, and bioactivity prediction. Structural Chemistry (2022) https://doi.org/10.1007/s11224-022-01959-3.

Book
Format: Author. Year. Title of book. Publisher, ISBN, Edition.
Example: Zothantluanga JH (2022) How to write a research paper? Springer, 9788194138860, 1st Edition.

Book chapter
Format: Author. Year. Title of a book chapter. Title of Book, Editor of Book, Publisher, ISBN, Edition.

Example: Zothantluanga JH (2022) Phytochemical screening of blueberries. In: Sciences of Phytochemistry, Editor: Umar AK, Springer, 9788194138860, 1st Edition.

Website
Format: Title. URL. Date.
Example: WHO Coronavirus (COVID-19) Dashboard. https://covid19.who.int/. Accessed 14 June 2022.

Reference category (If possible, authors should cite the latest references with the exception of review papers or few research fields with less publications)

  1. Too old (before 2000)
  2. Old (2001-2010)
  3. New (2011-2020)
  4. Fresh (after 2021)

Authorship policy
In terms of planning the study design, data analysis, statistical analysis, software, executing work, writing, and editing, a significant contribution should be made by all contributing authors such as the first author, co-authors, and corresponding authors. Authors are encouraged to get familiar with the Committee on Publication Ethics (COPE) guidelines.

Corresponding author
The corresponding author will take the responsibility of communicating with the editors from the initial submission till publication. Depending on the requirement, there may be two corresponding authors. In case of two corresponding authors, the asterisk '*' sign should accompany their names in the manuscript and the initials of the authors should accompany their email address in the manuscript.

Change of authorship
During the review process, the corresponding author may make a request to the editor-in-chief to make changes in the authorship with valid reasons to justify the request. Addition or deletion of authors after acceptance of manuscript is not allowed.

Plagiarism policy
If possible, authors are requested to submit a plagiarism report from a commercial software (or from a free online server). For all types of articles, the plagiarism percentage should be kept as low as possible (maximum upper limit 20% excluding references). Even if the plagiarism percentage remains below 20%, the authors may be further asked to reduce the plagiarism to increase the authenticity of the manuscript.

Ethic policy
Studies involving animal, cell lines, or human participants should be carried out keeping in mind the standard guidelines set by OECDCPCSEAICH, Animal Welfare Board of IndiaICMJE recommendations, as well as other organizations. Ethical clearance with proper documents should be obtained from the concerned authority (for example, Institutional Animal Ethics Committee) to carry out the studies. Also, sufficient details regarding the document numbers should be mentioned in the manuscript. 

Plants
Medicinal plants should be collected in minimal amounts to avoid exploitation of natural resources and to avoid disturbing the local ecosystem. The World Health Organization guidelines on good agricultural and collection practices for medicinal plants should be followed.

Retraction policy
Retraction guidelines provided by the Committee on Publication Ethics will be followed. A notice of retraction will be given to a paper if the findings are unreliable, unethical, plagiarized, or manipulated. To maintain integrity, the retracted paper will remain visible on the journal page. However, a notice of retraction will accompany the paper.

Guidelines for editors
The editor-in-chief will be responsible for searching suitable reviewers that are experts in the concerned field. If potential reviewers are suggested by the authors, the editor-in-chief should contact the suggested reviewers. Following SciPhy's double-blind peer-review policy, the editor should make sure that the reviewer completes their task within 2-4 weeks. After peer-review, the editor-in-chief will evaluate the reviewer comments for a decision. Following this, the editor-in-chief will contact the corresponding author of the manuscript to inform about the decision and to check the status of their submitted manuscript in the online submission system. In case of revision, the editor-in-chief should direct the authors to submit the corrected manuscript to the editor-in-chief. After revision, the editor-in-chief will make the final editorial assessment. If the manuscript is accepted for publication, the editor-in-chief will send a galley proof to the authors. The final corrected proofs must be submitted to the editor-in-chief. Following this, the manuscript will be published online.

The name of the editor will be made available on the first page of the published paper.

Guidelines for reviewers

  1. Reviewers for SciPhy should make an unbiased decision on the manuscript.
  2. Reviewers should not allow any external/personal factors to influence their decision.
  3. Rather than direct rejection, reviewers should search for ways to improve the manuscript.
  4. Reviewers should provide clear suggestions and directions for improving the manuscript.
  5. Reviewers should check the validity of the references.
  6. Reviewers should check the scientific correctness of each statement.
  7. Reviewers should cross check the in-text citations with the cited references.
  8. Reviewers must keep their task confidential till the papers are published.
  9. Reviewers should inform the editor-in-chief/editor if there are any conflicting interest.

Benefits for reviewers

  1. In recognition to their contributions, the name of the reviewer will be made available on the first page of the published paper. Reviewers can also choose to remain anonymous.
  2. A certificate of appreciation will also be provided to reviewers who had successfully completed their task.
  3. Papers communicated by reviewers of SciPhy will be provided with a special fast-track review to speed up the final decision.

Proposing Special Issues
To propose a special issue, a proposal should be submitted to SciPhy through the journal's email address. The proposal for a special issue should be submitted in a single MS Word file and it must contain:

  1. Title of the special issue
  2. Theme/Scope/Areas covered by the special issue
  3. Significance of the special issue
  4. CV of Guest Editors
  5. Projected Timeline (Call for papers and submission deadline)

Submission of manuscript for Special Issues

  • Authors should use the online submission system to submit their manuscripts.
  • Under New submission, authors should select the special issue under the issue option.
  • The Editor-in-Chief of SciPhy will initially evaluate the authenticity of all submitted manuscripts.
  • Following this, the manuscript will be handed to the Guest Editor.
  • The Guest Editor will be responsible for handling the peer-review process of all the manuscripts.
  • All manuscripts that are accepted by the Guest Editor shall be submitted to SciPhy for publication.

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Dr Meilinda setya praceka (Google Scholar)
Department of Pharmacy, Faculty of Pharmacy, Universitas Halim Sanusi, Bandung – 40273, Indonesia

Dr Igbokwe Mariagoretti Chikodili (Google Scholar)
Pharmacy Department, National Orthopaedic Hospital, Enugu 400103, Nigeria

Dr Mary Ololade Akinlade (Google Scholar)
Department of Pharmacognosy and Traditional Medicine, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka

Dr Ahmed Abd El-Moniem Amer (Google Scholar)
Department of Clinical Pharmacy, Damanhur Military Hospital, Behiera, Egypt

Dr Arpita Paul (Google Scholar)
Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh 786004, Assam, India

Dr Ngurzampuii Sailo (Google Scholar)
Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh 786004, Assam, India

Dr K. Rosangzuala (Google Scholar)
CSIR-Indian Institute of Chemical Technology (IICT), Hyderabad, Telangana, India

Dr Dhritiman Roy (Google Scholar)
Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh 786004, Assam, India

Dr Kavitha Karthik Pai (Google Scholar)
Department of Dietetics and Applied Nutrition, WGSHA, Manipal University, Manipal 576104, Karnataka, India

Dr Kalyani Pathak (Google Scholar)
Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh 786004, Assam, India

Dr Zonunmawii (Google Scholar)
Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh 786004, Assam, India

Dr Padmashree Das (Google Scholar)
Centre for Biotechnology & Bioinformatics, Dibrugarh University, Dibrugarh 786004, Assam, India

Dr Ejiofor InnocentMary IfedibaluChukwu (Google Scholar)
Department of Pharmacognosy and Traditional Medicine, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka-420110

Dr Faruk Jayanto Kelutur (Google Scholar)
Department of Chemistry, Pattimura University, Ambon, Indonesia

Dr Dipankar Nath (Google Scholar)
Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh 786004, Assam, India

Dr Malita Sarma (Google Scholar)
Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh 786004, Assam, India

Dr Keerthic Aswin (Google Scholar)
Institute of Genomics and Integrative Biology, New Delhi, India

Dr Lima Patowary (Google Scholar)
Department of Pharmaceutical Chemistry, Girijananda Chowdhury Institute of Pharmaceutical Sciences, Guwahati, Assam, India

Dr Mohamed El Fadili (Google Scholar)
Engineering Materials, Modeling and Environmental Laboratory, Faculty of Sciences Dhar El Mehraz, Sidi Mohammed Ben Abdellah University, BP 1796 Atlas, Fez 30000, Morocco

Dr K. Rosangzuala (Google Scholar)
CSIR-Indian Institute of Chemical Technology (IICT), Hyderabad, Telangana, India

Dr Lalduhsanga Pachuau (Google Scholar)
Department of Pharmaceutical Science, Assam University, Silchar – 788011, India

Dr Sudarshana Borah (Google Scholar)
Department of Pharmaceutical Sciences, University of Science and Technology, Meghalaya 793101, India

Dr Keerthic Aswin (Google Scholar)
CSIR-GATE JRF, Institute of Genomics and Integrative Biology, New Delhi, India

Dr Abd. Kakhar Umar (Google Scholar)
Department of Pharmaceutics and Pharmaceutical Technology, Padjadjaran University, Indonesia

Dr A. Lalzamliana (Google Scholar)
Novartis, Hyderabad, India

Dr Sanchaita Rajkhowa (Google Scholar)
Centre for Biotechnology and Bioinformatics, Dibrugarh University, Assam, India

Dr Mithun Rudrapal (Google Scholar)
Department of Pharmaceutical Chemistry, Rasiklal M. Dhariwal Institute of Pharmaceutical Education & Research, Maharashtra, India

Any enquiry related to the journal, please reach us through email below. Sciences of Phytochemistry editorial's email: sciphy@etflin.com

Office: Sungai Manonda Street, Duyu, Tatanga,
Palu City 94225, Indonesia.
WhatsApp: +62 82216335184
Publisher email: halo@etflin.com

Peer-review Process

After submission of a manuscript, one of the editorial members will examine the quality of the manuscript. If the manuscript falls within the journal scope and showed high quality content, the editor will assign a minimum of two reviewers for the manuscript. After peer-review, the editor will make a decision based on the reviewer comments and recommendation. The decision made by the editor will be final. The journal follows a double-blind peer-review wherein the information of reviewers and authors are blinded from each other during the entire peer-review process. Please take a look at the Manuscript Lifecycle for detailed information.

Open Access Policy

All papers published in the journal are freely accessible immediately after publication. The papers are freely available to read, shared, and reproduced in any form with proper citation to the original work. Open access is a property of individual works and community standards that will enforce proper attribution and responsible use of the published work.

Author Charges

Publishing a paper in the journal is free. The journal do not take submission fees, editorial processing charges, article processing charges, page charges, or color charges.

Licensing Terms

The journal is licensed under the Creative Commons Attribution (CC BY) 4.0 International License. Detailed Licences Policy

Plagiarism

Plagiarism is not tolerated in ETFLIN journals. Plagiarism is defined as the act of copying words, ideas, images, or data from another source, including your own publications, without crediting the original source. Text copied from another source must be reused between quotation marks, and the original source must be cited. If the design of a study, or the style or language of the article, was inspired by past research, it must be fully cited.

The industry standard program Turnitin is used to check all ETFLIN submissions for plagiarism. The manuscript may be rejected if plagiarism is discovered during the peer review process. If plagiarism is discovered after publication, an inquiry will be conducted and appropriate action will be taken in accordance with our policy.

Latest Articles

Research Article

In-vitro and in-silico evaluation of Brugmansia sauveolens' ability to treat asthma

by Shouvik Kumar Nandy, Shikha Thakur
Sciences of Phytochemistry; Vol 2, Issue 1; 01 June 2023
https://doi.org/10.58920/sciphy02010159

Abstract: Asthma is a common chronic inflammatory disease of the airways. The airway epithelium produces bioactive cellular mediators that trigger the chronic inflammatory response. These mediators then attract and activate inflammatory cells in the airways of the lungs and release more biochemical mediators. [...] Show more.
Abstract: Asthma is a common chronic inflammatory disease of the airways. The airway epithelium produces bioactive cellular mediators that trigger the chronic inflammatory response. These mediators then attract and activate inflammatory cells in the airways of the lungs and release more biochemical mediators. With several benefits, such as a significant reduction in the cost and time of drug discovery as well as the use of laboratory animals, in-silico studies have grown to be an important and simple method for examining various chemical compounds against various targets. One of the common herbs found in the local Himalayan area is Brugmansia sauveolens, known as Datura, which is a source of tropane alkaloids and asthma can be effectively managed with alkaloids. Using a Soxhlet extractor, the collected plant components were first extracted with petroleum ether (to remove fats) followed by methanol. Online technologies like PASS Online, Molinspiration, SEA, SWISS, and SLAP data were used for a variety of in-silico predictions. After that, we tested the ability of Brugmansia extracts to reduce inflammation using an in-vitro approach. Rat RBC membrane lyses were stabilized using the plant extract fractions. The outcomes were also compared with aspirin (a common anti-inflammatory drug). Bioinformatics techniques were used to detect structural activity. After investigating all the data It was shown that B. sauveolens had anti-asthmatic activity. Show less...

Review

Lawsonia inermis Linn: A breakthrough in cosmeceuticals

by Siuli Sen, Malita Sarma Borthakur, Dipak Chetia
Sciences of Phytochemistry; Vol 2, Issue 1; 31 May 2023
https://doi.org/10.58920/sciphy02010128

Abstract: Herbal cosmetics are formulated using different cosmetic ingredients to form the base in which one or more herbal ingredients are used to cure various skin ailments. The name suggests that herbal cosmetics are natural and free from all the harmful synthetic chemicals that otherwise may be toxic to t [...] Show more.
Abstract: Herbal cosmetics are formulated using different cosmetic ingredients to form the base in which one or more herbal ingredients are used to cure various skin ailments. The name suggests that herbal cosmetics are natural and free from all the harmful synthetic chemicals that otherwise may be toxic to the skin. Compared to other beauty products, natural cosmetics are safe to use. Cosmeceuticals are cosmetic-pharmaceutical hybrid products intended to improve the health and beauty of the skin by providing a specific result. There are numerous herbs available naturally that have different uses in cosmetic preparations for skincare, hair care, and as antioxidants. The current study included a review and authentication of the various aspects of the plant Lawsonia inermis. L. inermis, commonly known as henna. It has been cultivated for thousands of years for its leaves, which contain a natural dye molecule called lawsone that is commonly used to dye hair, skin, and fabrics. Henna has a long history of use in traditional medicine, where it has been used to treat a variety of ailments. In addition to its medicinal and cosmetic uses, henna has cultural and religious significance in many parts of the world and is commonly used to decorate the skin for weddings, festivals, and other special occasions. Because of these therapeutic properties, the L. inermis plant can be used as a medicine against a wide range of pathogenic organisms and diseases. This review covers the phytochemistry, pharmacological properties, and traditional uses of the plant. Show less...

Research Article

Pharmacognostic Study and Hepatoprotective Activity of the Methanolic Extract and Fractions of Leaves of Picralima nitida Apocyanaceae

by Akinlade Mary Ololade, Fredrick Chinedu Anowi, Ajaghaku Amara Anwuchaepe, Ejiofor InnocentMary IfedibaluChukwu
Sciences of Phytochemistry; Vol 2, Issue 1; 29 May 2023
https://doi.org/10.58920/sciphy02010114

Abstract: Picralima nitida the only species in the genus Picralima belongs to the Apocyanaceae family. It is widely known for its medicinal purposes. The aim of the study was to investigate pharmacognostic parameters of the leaf and evaluate the hepatoprotective activity against carbon tetrachloride induced h [...] Show more.
Abstract: Picralima nitida the only species in the genus Picralima belongs to the Apocyanaceae family. It is widely known for its medicinal purposes. The aim of the study was to investigate pharmacognostic parameters of the leaf and evaluate the hepatoprotective activity against carbon tetrachloride induced hepatotoxicity using Swiss Albino mice. The physicochemical evaluation indicated 11.75% moisture content, 8.50% total ash, 9.50% acid insoluble ash, 4.00% water soluble ash, 13.75% alcohol extractive value and 11.00% water extractive value. Macroscopic analysis on the fresh leaves revealed an odourless green plant with bitter taste. Microscopic examination indicated the presence of calcium oxalate crystals, starch grains, epidermal cells, xylem, parenchyma cells, paracytic stomata and palisade tissue. Chemomicroscopic evaluation indicated the presence of oxalate crystals, starch grains, lignified tissues, tannins, cellulose, protein and oil. The acute toxicity result revealed that P. nitida had no adverse effect in Swiss Albino mice. The ethyl acetate fraction had hepatoprotective ability on liver enzymes (alanine transaminase, aspartate aminotransferase, alkaline phosphatase) and can produce the same result as ascorbic acid (standard). Show less...

Research Article

Inhibitory effect of herbal compounds on the Oxygen-insensitive NADPH nitro reductase enzyme of metronidazole-resistant Helicobacter pylori

by Mohammadreza Saeed, Anoosh Eghdami
Sciences of Phytochemistry; Vol 2, Issue 1; 28 May 2023
https://doi.org/10.58920/sciphy02010098

Abstract: Helicobacter pylori is a significant risk factor for chronic gastritis, gastric ulcers, and gastric cancer. The purpose of this article is to investigate the potential impact of fifty herbal compounds derived from Ginger and Parsley plants, known for their antibacterial properties on the Oxygen-inse [...] Show more.
Abstract: Helicobacter pylori is a significant risk factor for chronic gastritis, gastric ulcers, and gastric cancer. The purpose of this article is to investigate the potential impact of fifty herbal compounds derived from Ginger and Parsley plants, known for their antibacterial properties on the Oxygen-insensitive NADPH nitro reductase enzyme of metronidazole-resistant H. pylori. In the present study, the information on the structure of compounds, the H. pylori resistant to metronidazole enzyme, myristicin, and shogaol derivatives were obtained from databases such as ZINC15, RCSB (Protein Data Bank), and PubChem, respectively. Finally, molecular docking was performed with iGemdock2.1 and Molegro Virtual Docker. After molecular docking, four out of the fifty phytocompounds showed the lowest energy and the highest number of interactions with the amino acids at the binding sites. Among these four phytocompounds, the best phytocompound was N-Vanillyloctanamide derived from Ginger. Our molecular docking study suggests that ginger can be introduced as a potential candidate to inhibit the growth of H. pylori. Show less...

Review

Prolonged space flight: Adverse health effects and treatment options with medicinal plants and natural products

by Nayana Bhuyan, Shatabdi Ghose, Smitashikha Bhattacharya, Tapash Chakraborty
Sciences of Phytochemistry; Vol 2, Issue 1; 24 May 2023
https://doi.org/10.58920/sciphy02010082

Abstract: Exposure to zero gravity causes many physiological changes which may result to affect the health of people involved in space travel. The current review summarizes current knowledge on the start and progression of space motion sickness, bone loss, muscle loss, cardiovascular disorders, respiratory pr [...] Show more.
Abstract: Exposure to zero gravity causes many physiological changes which may result to affect the health of people involved in space travel. The current review summarizes current knowledge on the start and progression of space motion sickness, bone loss, muscle loss, cardiovascular disorders, respiratory problems, and neuronal and hormonal problems. Around 70% of astronauts suffer from space adaption syndrome, fluid changes, and head motions. It has also been suggested that otolith asymmetries and Coriolis cross-coupling stimulation are the main causes of space motion sickness. The findings reveal that space flight directly affects the body's normal functioning. Despite an intense training routine, a study of historical data from piloted flights discovered that slow degradation of bone and muscle tissue, along with fluid losses, can eventually lead to kidney stones, musculoskeletal problems, bone fractures, and even problems with other organs of the body. Due to such problems focus is given to curing these problems associated with space travel. Medicines that are used in space and medicinal plants like Spirulina, and Ginseng that are of use for the treatment of these problems associated with space travel are discussed along with the treatment options available for such problems in space and the cautions that must be followed. Also, the herbal medication that can be used in outer space is taken into account. The findings of this study state the necessary precaution that needs to be taken by astronauts in outer space and also provides information for future research to be done on solving these problems. Show less...

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